ARL4A Antibody

Datasheet

Code	CSB-PA002085HA01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ARL4A Polyclonal antibody

Uniprot No.

P40617

Target Names

ARL4A

Alternative Names

ADP ribosylation factor like 4 antibody; ADP ribosylation factor like 4A antibody; ADP ribosylation factor like GTPase 4A antibody; ADP-ribosylation factor-like protein 4A antibody; ARL 4 antibody; ARL4 antibody; Arl4a antibody; ARL4A_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human ADP-ribosylation factor-like protein 4A protein (2-200AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ARL4A Antibody (Product code: CSB-PA002085HA01HU) is Non-conjugated. For ARL4A Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA002085HB01HU	ARL4A Antibody, HRP conjugated	ELISA
FITC	CSB-PA002085HC01HU	ARL4A Antibody, FITC conjugated
Biotin	CSB-PA002085HD01HU	ARL4A Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form.

Gene References into Functions

Deletion of the ARL4A-interacting region of GCC185 results in inability to maintain Golgi structure and modulate endosome-to-Golgi transport. PMID: 22159419
membrane targeting of ELMO via Arl4A promotes cytoskeletal reorganization including membrane ruffling and stress fiber disassembly via an ELMO-DOCK1800-Rac signaling pathway. PMID: 21930703
The loss of PTEN was shown to lead to increased levels of ARF4L protein but no change in transcript levels. The ARF4L transcript preferentially localized to the polysomal compartment after PTEN loss in glioma. PMID: 18240926

Subcellular Location

Cell membrane. Cytoplasm. Nucleus, nucleolus. Note=Localization in the nucleolus is dependent by nucleotide binding.

Protein Families

Small GTPase superfamily, Arf family

Database Links

HGNC: 695

OMIM: 604786

KEGG: hsa:10124

STRING: 9606.ENSP00000349250

UniGene: Hs.245540

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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