ARL4A Antibody

Code CSB-PA002085GA01HU
Size US$685
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Product Details

Uniprot No. P40617
Target Names ARL4A
Alternative Names ADP ribosylation factor like 4 antibody; ADP ribosylation factor like 4A antibody; ADP ribosylation factor like GTPase 4A antibody; ADP-ribosylation factor-like protein 4A antibody; ARL 4 antibody; ARL4 antibody; Arl4a antibody; ARL4A_HUMAN antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human ARL4A
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form.
Gene References into Functions
  1. Deletion of the ARL4A-interacting region of GCC185 results in inability to maintain Golgi structure and modulate endosome-to-Golgi transport. PMID: 22159419
  2. membrane targeting of ELMO via Arl4A promotes cytoskeletal reorganization including membrane ruffling and stress fiber disassembly via an ELMO-DOCK1800-Rac signaling pathway. PMID: 21930703
  3. The loss of PTEN was shown to lead to increased levels of ARF4L protein but no change in transcript levels. The ARF4L transcript preferentially localized to the polysomal compartment after PTEN loss in glioma. PMID: 18240926
Subcellular Location Cell membrane, Cytoplasm, Nucleus, nucleolus
Protein Families Small GTPase superfamily, Arf family
Database Links

HGNC: 695

OMIM: 604786

KEGG: hsa:10124

STRING: 9606.ENSP00000349250

UniGene: Hs.245540

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