ARL5B Antibody

Code CSB-PA002091GA01HU
Size US$685
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Product Details

Uniprot No. Q96KC2
Target Names ARL5B
Alternative Names ARL5B antibody; ARL8 antibody; ADP-ribosylation factor-like protein 5B antibody; ADP-ribosylation factor-like protein 8 antibody
Raised in Rabbit
Species Reactivity Human,Mouse
Immunogen Human ARL5B
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB,IHC
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Citations

The FTO/miR‐181b‐3p/ARL5B signaling pathway regulates cell migration and invasion in breast cancer. Y Xu,Cancer Commun (Lond),2020

Applications: Westernblotting
Antibody dilution factor: 1:1000
Sample type: Breast cancer cells
Review: The protein leve lof ARL5B in FTO-silencedor-overexpressing SKBR3 and MDA-MB453cells.
PMID: 32805088

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Target Data

Function Binds and exchanges GTP and GDP.
Gene References into Functions
  1. Depletion of either Arl5b or AP4 results in the accumulation of APP. PMID: 28000370
  2. Arl5b is a trans-golgi-network-localised small G protein that plays a key role in regulating transport along the endosome-trans-golgi network pathway PMID: 22245584
  3. Arl8 and SKIP are required for lysosomes to distribute away from the microtubule-organizing center. We identify two kinesin light chain binding motifs in SKIP that are required for lysosomes to accumulate kinesin-1 and redistribute to the cell periphery. PMID: 22172677
  4. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 20932310
  5. ARL8 contains six exons and five introns, and encodes a 179 amino acid protein that shares homology to the other ARL proteins. PMID: 12853149
  6. Observational study of gene-disease association. (HuGE Navigator) PMID: 16385451

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Protein Families Small GTPase superfamily, Arf family
Database Links

HGNC: 23052

OMIM: 608909

KEGG: hsa:221079

STRING: 9606.ENSP00000366487

UniGene: Hs.25362

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