ARMT1 Antibody

Code CSB-PA867178LA01HU
Size US$166
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  • Western blot
    All lanes: ARMT1 antibody at 0.6µg/ml
    Lane 1: MCF-7 whole cell lysate
    Lane 2: A431 whole cell lysate
    Lane 3: 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 52 kDa
    Observed band size: 52 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA867178LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA867178LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA867178LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA867178LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ARMT1 Polyclonal antibody
Uniprot No.
Target Names
ARMT1
Alternative Names
ARMT1 antibody; C6orf211Damage-control phosphatase ARMT1 antibody; EC 3.1.3.- antibody; Acidic residue methyltransferase 1 antibody; Protein-glutamate O-methyltransferase antibody; EC 2.1.1.- antibody; Sugar phosphate phosphatase ARMT1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein-glutamate O-methyltransferase protein (2-250AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ARMT1 Antibody (Product code: CSB-PA867178LA01HU) is Non-conjugated. For ARMT1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA867178LB01HU ARMT1 Antibody, HRP conjugated ELISA
FITC CSB-PA867178LC01HU ARMT1 Antibody, FITC conjugated
Biotin CSB-PA867178LD01HU ARMT1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
Gene References into Functions
  1. Studies show that acidic residue methyltransferase 1 (Armt1) has a vital role in regulation of the DNA damage response likely through its ability to O-methylate glutamyl residues of the DNA repair factor proliferating cell nuclear antigen (PCNA). PMID: 26450907
  2. Armt1 protein specifically targets proliferating cell nuclear antigen (PCNA) in breast cancer cells, predominately methylating glutamate side chains. PMID: 25732820
  3. C6ORF211 correlates with proliferation and clinical outcome in tumors. PMID: 21552322
Protein Families
ARMT1 family
Database Links

HGNC: 17872

OMIM: 616332

KEGG: hsa:79624

STRING: 9606.ENSP00000356263

UniGene: Hs.15929

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