ARMT1 Antibody

Code CSB-PA867178LA01HU
Size US$166
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  • Western blot
    All lanes: ARMT1 antibody at 0.6µg/ml
    Lane 1: MCF-7 whole cell lysate
    Lane 2: A431 whole cell lysate
    Lane 3: 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 52 kDa
    Observed band size: 52 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA867178LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA867178LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA867178LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA867178LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ARMT1 Polyclonal antibody
Uniprot No.
Target Names
ARMT1
Alternative Names
ARMT1 antibody; C6orf211Damage-control phosphatase ARMT1 antibody; EC 3.1.3.- antibody; Acidic residue methyltransferase 1 antibody; Protein-glutamate O-methyltransferase antibody; EC 2.1.1.- antibody; Sugar phosphate phosphatase ARMT1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein-glutamate O-methyltransferase protein (2-250AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ARMT1 Antibody (Product code: CSB-PA867178LA01HU) is Non-conjugated. For ARMT1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA867178LB01HU ARMT1 Antibody, HRP conjugated ELISA
FITC CSB-PA867178LC01HU ARMT1 Antibody, FITC conjugated
Biotin CSB-PA867178LD01HU ARMT1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function
Metal-dependent phosphatase that shows phosphatase activity against several substrates, including fructose-1-phosphate and fructose-6-phosphate. Its preference for fructose-1-phosphate, a strong glycating agent that causes DNA damage rather than a canonical yeast metabolite, suggests a damage-control function in hexose phosphate metabolism. Has also been shown to have O-methyltransferase activity that methylates glutamate residues of target proteins to form gamma-glutamyl methyl ester residues. Possibly methylates PCNA, suggesting it is involved in the DNA damage response.
Gene References into Functions
  1. Studies show that acidic residue methyltransferase 1 (Armt1) has a vital role in regulation of the DNA damage response likely through its ability to O-methylate glutamyl residues of the DNA repair factor proliferating cell nuclear antigen (PCNA). PMID: 26450907
  2. Armt1 protein specifically targets proliferating cell nuclear antigen (PCNA) in breast cancer cells, predominately methylating glutamate side chains. PMID: 25732820
  3. C6ORF211 correlates with proliferation and clinical outcome in tumors. PMID: 21552322
Protein Families
ARMT1 family
Database Links

HGNC: 17872

OMIM: 616332

KEGG: hsa:79624

STRING: 9606.ENSP00000356263

UniGene: Hs.15929

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