ARNT2 Antibody

1. The single nucleotide polymorphisms rs4778599 in the gene encoding aryl hydrocarbon receptor nuclear translocator 2 (ARNT2), showed an association that survived correction for multiple testing with emotion recognition of audio-visual stimuli in women PMID: 29194499
2. Attenuated ARNT2 expression in HCC827 cells greatly promoted tumor growth. PMID: 25613063
3. nominal associations were found between autism spectrum disorder scores and single-nucleotide polymorphisms in OXT, ARNT2 and CD38 PMID: 24635660
4. Data suggest that selected human SIM1 (single-minded homolog 1) variants exhibit poor dimerization with ARNT2 and anomalous intracellular localization; these data were used to predict 'hot-spot' in SIM1/SIM2 (residues 290-326) critical for function. PMID: 24814368
5. These results provide insight into the mechanisms of NPAS4/ARNT dimerisation and transcriptional activation. PMID: 24465693
6. mutation of ARNT2 results in absence of detectable levels of ARNT2 transcript and protein from patient fibroblasts compared with controls, consistent with nonsense-mediated decay of the mutant transcript and loss of ARNT2 function. PMID: 24022475
7. In white males, rs4072568 in ARNT2 was also associated with BMI (P = 9 x 10(-4)) and % body fat (P = 0.001). PMID: 21512513
8. ARNT2 might play an important role in the modulation of HIF-1-regulated signaling and metabolism. PMID: 21945317
9. promotes differentiation of IL-22-producing CD4(+) T-cells PMID: 20706985
10. There is no association of ARNT2 gene with cleft palate only (n = 45) and cleft lip/palate (n = 37). PMID: 12210012
11. We thus propose that NDN regulates neuronal function and hypoxic response by regulating the activities of the ARNT2:SIM1 and ARNT2:HIF1alpha dimers, respectively. PMID: 17826745
12. a possible use of ARNT2 and GST A1 as prognostic breast cancer biomarkers. PMID: 17899366

Show More

Hide All

HGNC: 16876

OMIM: 606036

KEGG: hsa:9915

STRING: 9606.ENSP00000307479

UniGene: Hs.459070