AURKAIP1 Antibody

Datasheet

Code	CSB-PA794202
Size	US$166
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Image	Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human testis tissue, Primary antibody: CSB-PA794202(AURKAIP1 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details
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Target Background

Product Details

Uniprot No.

Q9NWT8

Target Names

AURKAIP1

Alternative Names

28S ribosomal protein S38 antibody; AIP antibody; AKIP_HUMAN antibody; AURKA interacting protein antibody; AURKA-interacting protein antibody; AURKAIP 1 antibody; Aurkaip1 antibody; Aurora A kinase interacting protein antibody; Aurora kinase A interacting protein 1 antibody; Aurora kinase A-interacting protein antibody; FLJ20608 antibody; mitochondrial antibody; MRP-S38 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Fusion protein of Human AURKAIP1

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation.

Gene References into Functions

Encodes a mitochondrial protein PMID: 22356826
Aurora-A protein increased in stomach cancer cells in response to cisplatin and was degraded upon combined treatment with capsaicin with cisplatin. PMID: 21932983
Results describe the identification of a novel negative regulator of Aurora-A, named AIP (Aurora-A kinase Interacting Protein). PMID: 12244051
Phe31Ile polymorphism in Aurora A may be a genetic modifier for developing breast carcinoma. PMID: 15271856
We propose that AURKAIP1 might function upstream of the Az1 by enhancing the binding affinity of Az1 to Aurora-A to promote recognition, targeting to proteasome and subsequent degradation. PMID: 17452972
AKURA phosphorylation of AIP and stabilization of the enzyme-substrate complex are reported. PMID: 17957726
GSK-3beta modulates the early mitotic Aurora-A level through binding and phosphorylating AIP. PMID: 18391981
Plk1 controls Aurora A localization and function by regulating cellular levels of hBora. PMID: 18521620
Aurora A is necessary for the maintenance of the mitotic delay induced in response to microtubule-perturbing agents. PMID: 19221504

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Subcellular Location

Mitochondrion. Nucleus.

Protein Families

Mitochondrion-specific ribosomal protein mS38 family

Tissue Specificity

Ubiquitously expressed and especially highly expressed in heart, skeletal muscle and testis.

Database Links

HGNC: 24114

OMIM: 609183

KEGG: hsa:54998

STRING: 9606.ENSP00000319778

UniGene: Hs.632515

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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