AVIL Antibody

Datasheet
Code CSB-PA002464LA01HU
Size US$299
Uniprot No. O75366
Image
  • Western Blot
    Positive WB detected in: HepG2 whole cell lysate
    All lanes: AVIL antibody at 1:2000
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 93, 92 kDa
    Observed band size: 93 kDa
Immunogen Recombinant Human Advillin protein (623-819AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, WB; Recommended dilution: WB:1:1000-1:5000
Relevance Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Advillin (p92), AVIL
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Research Area Neuroscience
Target Names AVIL
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis.
Subcellular Location Cytoplasm, cytoskeleton, Cell projection, Cell projection, axon
Protein Families Villin/gelsolin family
Tissue Specificity Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus.
Database Links

HGNC: 14188

OMIM: 613397

KEGG: hsa:10677

STRING: 9606.ENSP00000257861

UniGene: Hs.584854

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