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B3GNT3 Antibody

Datasheet
Code CSB-PA002501GA01HU
Size $600
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Product Details

Uniprot No.
Q9Y2A9
Target Names
B3GNT3
Alternative Names
B3GNT3 antibody; B3GALT8 antibody; TMEM3 antibody; UNQ637/PRO1266N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 antibody; EC 2.4.1.149 antibody; Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase antibody; EC 2.4.1.146 antibody; Beta-1,3-galactosyltransferase 8 antibody; Beta-1,3-GalTase 8 antibody; Beta3Gal-T8 antibody; Beta3GalT8 antibody; b3Gal-T8 antibody; Beta-3-Gx-T8 antibody; Core 1 extending beta-1,3-N-acetylglucosaminyltransferase antibody; Core1-beta3GlcNAcT antibody; Transmembrane protein 3 antibody; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 8 antibody; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 antibody; BGnT-3 antibody; Beta-1,3-Gn-T3 antibody; Beta-1,3-N-acetylglucosaminyltransferase 3 antibody; Beta3Gn-T3 antibody; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 8 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human B3GNT3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Protocols
ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Has activity for type 2 oligosaccharides. Also acts as a core1-1,3-N-acetylglucosaminyltransferase (Core1-beta3GlcNAcT) to form the 6-sulfo sialyl Lewis x on extended core1 O-glycans.
Gene References into Functions
  1. This study demonstrated that elevated B3GNT3 expression is associated with pelvic lymph node metastasis and poor outcome in early-stage cervical cancer patients. PMID: 26709519
  2. B3GNT3 predicts a favorable cancer behavior of neuroblastoma and suppresses malignant phenotypes by modulating mucin-type O-glycosylation and signaling in neuroblastoma cells. PMID: 24118321
Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein Families
Glycosyltransferase 31 family
Tissue Specificity
Expressed in colon, jejunum, stomach, esophagus, placenta and trachea.
Database Links

HGNC: 13528

OMIM: 605863

KEGG: hsa:10331

STRING: 9606.ENSP00000321874

UniGene: Hs.657825

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