BFAR Antibody

Code CSB-PA002678ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA002678ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA002678ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) BFAR Polyclonal antibody
Uniprot No.
Target Names
BFAR
Alternative Names
BFAR; BAR; RNF47; Bifunctional apoptosis regulator; RING finger protein 47
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Bifunctional apoptosis regulator protein (1-140AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Apoptosis regulator. Has anti-apoptotic activity, both for apoptosis triggered via death-receptors and via mitochondrial factors.
Gene References into Functions
  1. Data show that p75NTR and BFAR co-localized within the cytoplasm. PMID: 22566094
  2. post-translational regulation of the BI-1 protein by E3 ligase BAR contributes to the dynamic control of IRE1 signaling during endoplasmic reticulum stress PMID: 21068390
  3. Over-expression of BFAR Delta RING renders the heart more resistant to I/R injury and DOX-induced cardiotoxicity, and this protection correlates with reduced cardiomyocyte apoptosis. PMID: 18805781
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity
Expressed highly in brain, moderately in small intestine, weakly in testes and only faintly in liver and skeletal muscle. Not expressed in heart, kidney, lung and spleen.
Database Links

HGNC: 17613

KEGG: hsa:51283

STRING: 9606.ENSP00000261658

UniGene: Hs.435556

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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