BLID Antibody

Code CSB-PA818276ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA818276ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) BLID Polyclonal antibody
Uniprot No.
Target Names
BLID
Alternative Names
BH3-like motif containing; cell death inducer antibody; BH3-like motif-containing cell death inducer antibody; BLID antibody; BLID_HUMAN antibody; BRCC2 antibody; breast cancer cell 2 antibody; Breast cancer cell protein 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human BH3-like motif-containing cell death inducer protein (1-108AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Functions as a proapoptotic molecule through the caspase-dependent mitochondrial pathway of cell death.
Gene References into Functions
  1. Results showed that the expression of BLID is frequently downregulated in non-small cell lung tumors and cell lines and inversely correlates with miR-575 expression. PMID: 25728273
  2. loss of BLID may contribute to the progression of intraductal proliferation lesions to breast cancer. PMID: 24532431
  3. BRCC2 functions as a novel tumor suppressor in breast cancer and may be a potential therapeutic target for breast cancer management. PMID: 23928696
  4. Frequent loss of the BLID gene is observed in early-onset breast cancer. PMID: 21846966
  5. Tag single nucleotide polymorphisms near the BLID and LOC399959 genes are not susceptibility loci for high myopia in the Chinese Han population. PMID: 21031016
  6. BLID upregulation resulting from a novel IGH translocation is associated with childhood B-Cell precursor acute lymphoblastic leukemia. PMID: 20544842
  7. BLID is a new binding partner of Bcl-X(L) and a significant prognostic factor in breast cancer PMID: 20400521
  8. BRCC2 is a novel BH3-like domain-containing protein which induces apoptosis in a caspase-dependent manner PMID: 15069058
  9. BLID gene is assigned to 11p24.1. PMID: 18940476
  10. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) PMID: 19779542

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Subcellular Location
Cytoplasm. Mitochondrion. Note=Lower abundance in mitochondrion than in cytoplasm.
Tissue Specificity
Ubiquitously expressed.
Database Links

HGNC: 33495

OMIM: 608853

KEGG: hsa:414899

STRING: 9606.ENSP00000453153

UniGene: Hs.686109

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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