BTN3A2 Antibody, HRP conjugated

Code CSB-PA002874LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) BTN3A2 Polyclonal antibody
Uniprot No.
Target Names
BTN3A2
Alternative Names
BT3.2 antibody; BT3.3 antibody; BT3A2_HUMAN antibody; BTF4 antibody; BTN3A 2 antibody; BTN3A2 antibody; Butyrophilin protein antibody; Butyrophilin subfamily 3 member A2 antibody; Butyrophilin; subfamily 3; member A2 antibody; CD277 antibody; FLJ40011 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Butyrophilin subfamily 3 member A2 protein (30-248AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
Gene References into Functions
  1. CpG-specific DNA methylation of ADAMTSL2 and BTN3A2 at rheumatoid arthritis diagnosis can serve as a marker of treatment response. PMID: 28447857
  2. BTN3A2 genetic variants have role in gastric carcinogenesis. PMID: 28246015
  3. BTN3A2 rs9104 was strongly associated with genotype 1 hepatitis C infection. PMID: 25928882
  4. Three SNPs in BTN3A2 were associated with schizophrenia, rs12214031, rs9393709 and rs12199613. There was no interaction between these SNPs and HSV-1, CMV or toxoplasma exposure. PMID: 22966150
  5. Results suggest that BT3.2 butyrophilin expression by epithelial cells may modulates the intratumoral infiltration of immune cells. PMID: 22685580
  6. our results identify PRSS16 and BTN3A2, two genes thought to play important roles in regulating the immune response, as potentially novel susceptibility genes for Type I Deabetes. PMID: 19295542

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Protein Families
Immunoglobulin superfamily, BTN/MOG family
Tissue Specificity
Detected in T-cells and natural killer cells.
Database Links

HGNC: 1139

OMIM: 613594

KEGG: hsa:11118

STRING: 9606.ENSP00000348751

UniGene: Hs.376046

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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