RTRAF Antibody

Datasheet

Code	CSB-PA896684ESR2HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA896684ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) RTRAF Polyclonal antibody

Uniprot No.

Q9Y224

Target Names

RTRAF

Alternative Names

C14orf166 antibody; CGI 99 antibody; CGI-99 antibody; CGI99 antibody; Chromosome 14 open reading frame 166 antibody; CLE antibody; CLE7 antibody; CN166_HUMAN antibody; Homeobox prox 1 antibody; LCRP369 antibody; RLL motif containing 1 antibody; RLLM1 antibody; UPF0568 protein C14orf166 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human RNA transcription, translation and transport factor protein (1-244AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

RNA-binding protein involved in modulation of mRNA transcription by Polymerase II. Component of the tRNA-splicing ligase complex and is required for tRNA ligation. May be required for RNA transport.; (Microbial infection) In case of infection by influenza virus A (IVA), is involved in viral replication.

Gene References into Functions

C14ORF166 may represent a biomarker of pelvic lymph node metastasis in uterine cervical cancer PMID: 26219895
C14orf166, a cellular protein required for viral replication, is incorporated into influenza virus particles. PMID: 26864902
C14orf166 promotes bladder cancer cell proliferation and can be a novel prognostic biomarker for patients with bladder cancer. PMID: 26905879
C14orf166 could be a novel prognostic biomarker of breast cancer, it also contributes to cell proliferation by regulating G1/S transition. PMID: 26883017
Overexpression of chromosome 14 open reading frame 166 correlates with disease progression in nasopharyngeal carcinoma. PMID: 25964093
Silencing of CLE causes reduction of influenza A virus polymerase activity, viral RNA transcription and replication, virus titer, and viral particle production. PMID: 21900157
spatial interactions of hnRNPH1, NF45, and C14orf166 with HCVc174 likely modulate HCV or cellular functions during acute and chronic HCV infection PMID: 21823664
A novel protein CGI-99 is isolated, which may be involved in the functional regulation of human ninein in the centrosome structure and may also be important in brain development and tumorigenesis. PMID: 15147888
c14orf166 was identified asa novel metastasis-associated protein, and the roles of radixin, moesin and c14orf166 in pancreatic cancer metastasis deserve further investigations. PMID: 19152423

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Subcellular Location

Nucleus. Cytoplasm, cytosol. Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.; Nucleus. Cytoplasm.

Protein Families

RTRAF family

Tissue Specificity

Widely expressed. Expressed at high level in heart and skeletal muscle. Expressed at intermediate level in liver, pancreas, fetal brain and fetal lung. Weakly expressed in adult brain, adult lung, placenta, fetal liver and fetal kidney. Overexpressed in m

Database Links

HGNC: 23169

OMIM: 610858

KEGG: hsa:51637

STRING: 9606.ENSP00000261700

UniGene: Hs.534457

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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