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CD47｜Proteinase K｜EGFR｜BCMA｜PD-L1｜CD276｜ACE2｜TMPRSS2｜Exosome Isolation Kits
Your Good Partner in Biology Research
CD47｜Proteinase K｜EGFR｜BCMA｜PD-L1｜CD276｜ACE2｜TMPRSS2｜Exosome Isolation Kits
| Code | CSB-PA003498GA01HU |
| Size | US$685 |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Uniprot No. | Q3KP66 |
| Target Names | INAVA |
| Alternative Names | C1orf106 antibody; CA106_HUMAN antibody; Chromosome 1 open reading frame 106 antibody; FLJ10901 antibody; Uncharacterized protein C1orf106 antibody |
| Raised in | Rabbit |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Human C1orf106 |
| Immunogen Species | Homo sapiens (Human) |
| Isotype | IgG |
| Purification Method | Antigen Affinity purified |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Tested Applications | ELISA,WB |
| Protocols | ELISA Protocol Western Blotting(WB) Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function | Expressed in peripheral macrophages and intestinal myeloid-derived cells, is required for optimal PRR (pattern recognition receptor)-induced signaling, cytokine secretion, and bacterial clearance. Upon stimulation of a broad range of PRRs (pattern recognition receptor) such as NOD2 or TLR2, TLR3, TLR4, TLR5, TLR7 and TLR9, associates with YWHAQ/14-3-3T, which in turn leads to the recruitment and activation of MAP kinases and NF-kappa-B signaling complexes that amplifies PRR-induced downstream signals and cytokine secretion. |
| Gene References into Functions |
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| Subcellular Location | Nucleus, Cytoplasm |
| Tissue Specificity | Highly expressed in intestinal myeloid-derived cells and expressed in monocyte-derived macrophages upon induction by PRR activation. |
| Database Links |
HGNC: 25599 KEGG: hsa:55765 STRING: 9606.ENSP00000356311 UniGene: Hs.518997 |
