CABP7 Antibody

Code CSB-PA180621
Size US$297
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  • Western blot analysis of extracts from Jurkat cells, using CABP7 antibody.
  • Immunohistochemistry analysis of paraffin-embedded human heart tissue using CABP7 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CABP7 Polyclonal antibody
Uniprot No.
Target Names
CABP7
Alternative Names
CaBP7 antibody; CABP7_HUMAN antibody; Calcium binding protein CaBP7 antibody; Calcium-binding protein 7 antibody; CALN2 antibody; Calneuron 2 antibody; Calneuron II antibody; Calneuron-2 antibody; MGC129428 antibody; MGC129429 antibody; MGC57793 antibody; MGC94082 antibody; OTTMUSP00000005262 antibody; rCaBP7 antibody; RP23-280J3.1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human CABP7.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IHC 1:50-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity.
Gene References into Functions
  1. CaBP7 regulates lysosome clustering at the intercellular bridge during cytokinesis in HeLa cells. CaBP7 depletion induces lysosome mislocalization, extension of intercellular bridge lifetime, and cytokinesis failure. PMID: 25717182
  2. Data indicate that the Ca(2+)-bound form of calcium-binding protein 7 (CaBP7) N-terminal domain (NTD) is monomeric and exhibits an open conformation. PMID: 22989873
Subcellular Location
Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Cytoplasm, perinuclear region. Cell membrane; Single-pass type IV membrane protein.
Database Links

HGNC: 20834

KEGG: hsa:164633

STRING: 9606.ENSP00000216144

UniGene: Hs.643608

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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