CALHM3 Antibody

Code CSB-PA768231LA01HU
Size US$166
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  • Western Blot
    All lanes: CALHM3 antibody at 8µg/ml + Mouse kidney tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 40, 39 kDa
    Observed band size: 40, 55 kDa

  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA768231LA01HU at dilution of 1:100

  • Immunofluorescent analysis of U251 cells using CSB-PA768231LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CALHM3 Polyclonal antibody
Uniprot No.
Target Names
CALHM3
Alternative Names
CALHM3; FAM26A; Calcium homeostasis modulator protein 3; Protein A
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Calcium homeostasis modulator protein 3 protein (201-350AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CALHM3 Antibody (Product code: CSB-PA768231LA01HU) is Non-conjugated. For CALHM3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA768231LB01HU CALHM3 Antibody, HRP conjugated ELISA
FITC CSB-PA768231LC01HU CALHM3 Antibody, FITC conjugated
Biotin CSB-PA768231LD01HU CALHM3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.
Gene References into Functions
  1. This study failed to show an association between theeight SNPs of the CALHM3 genes and alzheimer disease. PMID: 20164573
Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein.
Protein Families
CALHM family
Tissue Specificity
Specifically expressed in circumvallate taste bud cells.
Database Links

HGNC: 23458

KEGG: hsa:119395

STRING: 9606.ENSP00000358798

UniGene: Hs.364624

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