CALN1 Antibody

Datasheet

Code	CSB-PA871605LA01HU
Size	US$166
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Image	Western blot All lanes: CALN1 antibody at 2µg/ml + Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 25, 30 kDa Observed band size: 25 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CALN1 Polyclonal antibody

Uniprot No.

Q9BXU9

Target Names

CALN1

Alternative Names

CaBP8 antibody; CABP8_HUMAN antibody; Calcium binding protein 8 antibody; Calcium binding protein antibody; Calcium binding protein CABP8 antibody; Calcium-binding protein 8 antibody; Caln1 antibody; Calneuron I antibody; Calneuron-1 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Calcium-binding protein 8 protein (1-192AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CALN1 Antibody (Product code: CSB-PA871605LA01HU) is Non-conjugated. For CALN1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA871605LB01HU	CALN1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA871605LC01HU	CALN1 Antibody, FITC conjugated
Biotin	CSB-PA871605LD01HU	CALN1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity. May play a role in the physiology of neurons and is potentially important in memory and learning.

Gene References into Functions

up regulation serum exosomal miR-675 and down regulation of CALN1 in tumor specimen was also found to be associated with the metastatic phenotype in osteosarcoma patients. PMID: 29626470
CALN1 gene encoding calneuron 1 had the strongest correlation with CYP11B2 (aldosterone synthase) among genes encoding Ca2+-binding proteins in Aldosterone-producing Adenoma. PMID: 29109191
this report has further supported for associations of genetic variants in the ITIH4 and CALN1 genes with schizophrenia and provided the first evidence that the variants regulate ITIH4 AND CALN1 expression in the dorsolateral prefrontal cortex PMID: 26991396
detected the first genome-wide significant association of schizophrenia with CALN1, which is a predicted target of MIR137, and thus provide new evidence for the associations between MIR137 targets and schizophrenia PMID: 26206863
The protein is most abundant in Purkinje cells of the cerebellum and principal neurons of the cortex and limbic brain whereas no expression in glial cells is apparent. PMID: 26116628
provide strong evidence that CALN1 is a target of miR-137. PMID: 26163462
CaBP7 and 8 possess a targeting mechanism that is unique amongst the CaBPs that may contribute to differential functional Ca(2+)-sensing by these family members. PMID: 19338761

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Subcellular Location

Golgi apparatus, trans-Golgi network membrane; Single-pass type IV membrane protein. Cytoplasm, perinuclear region. Cell membrane; Single-pass type IV membrane protein.

Tissue Specificity

Brain specific.

Database Links

HGNC: 13248

OMIM: 607176

KEGG: hsa:83698

STRING: 9606.ENSP00000378690

UniGene: Hs.592750

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Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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