CARD17 Antibody

Code CSB-PA680389
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA680389(CARD17 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA680389(CARD17 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
CARD17
Alternative Names
CAR17_HUMAN antibody; CARD 17 antibody; CARD17 antibody; Caspase 1 inhibitor antibody; Caspase recruitment domain containing protein 17 antibody; Caspase recruitment domain-containing protein 17 antibody; Caspase-1 inhibitor INCA antibody; Caspase1 inhibitor antibody; Inhibitory caspase recruitment domain (CARD) protein antibody; Inhibitory caspase recruitment domain protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide of Human CARD17
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation.
Gene References into Functions
  1. INCA is a novel intracellular regulator of procaspase-1 activation, involved in the regulation of pro-IL-1beta processing and its release during inflammation PMID: 15383541
Subcellular Location
Cytoplasm.
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 33827

OMIM: 609490

KEGG: hsa:440068

STRING: 9606.ENSP00000364859

UniGene: Hs.732627

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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