CARF Antibody

Code CSB-PA000866
Size US$100
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  • Western Blot analysis of HuvEc cells using ALS2CR8 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
CARF
Alternative Names
Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 8 antibody; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein antibody; Calcium response factor antibody; Calcium-response factor antibody; Calcium-responsive transcription factor antibody; CaRF antibody; CARTF_HUMAN antibody; Testis development protein NYD SP24 antibody; Testis development protein NYD-SP24 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human ALS2CR8.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence.
Gene References into Functions
  1. Data demonstrate that CARF is a new target of miR-451 that mediates its tumor suppressor function in normal and stressed biological states. PMID: 29321561
  2. Cloned as a calcium- and neural-selective transcriptional activator of the gene for Brain-Derived Neurotrophic Factor (BDNF). PMID: 11832226
Subcellular Location
Nucleus.
Database Links

HGNC: 14435

OMIM: 607586

KEGG: hsa:79800

STRING: 9606.ENSP00000316224

UniGene: Hs.444982

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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