CCDC170 Antibody, HRP conjugated

1. Findings demonstrate that CCDC170 plays an essential role in Golgi-associated microtubules organization and stabilization, and implicate a mechanism for how perturbations in the CCDC170 gene may contribute to the hallmark changes in cell polarity and motility seen in breast cancer. PMID: 28687497
2. Data suggest that rs2046210 SNPs located in the region of C6ORF97 (CCDC170)-estrogen receptor alpha (ESR1) might have substantial roles not only in carcinogenesis but also in progression toward a more aggressive phenotype in breast cancer patients. PMID: 25370037
3. Our findings suggest that ESR1 and C6orf97 gene polymorphism is associated with fracture and vertebral fracture risk in Chinese postmenopausal women. PMID: 24481879
4. ESR1-CCDC170 rearrangements are found in an aggressive subset of estrogen receptor-positive breast cancers PMID: 25099679
5. Variation in rs3757318 of C6orf97 is associated with breast cancer risk. PMID: 25338983
6. SNPs associated with breast cancer differ for Asian, European, and African ancestry groups PMID: 20661439

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HGNC: 21177

KEGG: hsa:80129

STRING: 9606.ENSP00000239374

UniGene: Hs.660044