CCDC170 Antibody

Datasheet

Code	CSB-PA815585LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: HepG2 whole cell lysate, PC-3 whole cell lysate All lanes: CCDC170 antibody at 5µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 83 kDa Observed band size: 83 kDa
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CCDC170 Polyclonal antibody

Uniprot No.

Q8IYT3

Target Names

CCDC170

Alternative Names

bA282P11.1 antibody; CC170_HUMAN antibody; CCDC170 antibody; Chromosome 6 open reading frame 97 antibody; Coiled coil domain containing protein C6orf97 antibody; Coiled-coil domain-containing protein 170 antibody; FLJ23305 antibody; Hypothetical protein LOC80129 antibody; LOC80129 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Coiled-coil domain-containing protein 170 protein (574-651AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CCDC170 Antibody (Product code: CSB-PA815585LA01HU) is Non-conjugated. For CCDC170 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA815585LB01HU	CCDC170 Antibody, HRP conjugated	ELISA
FITC	CSB-PA815585LC01HU	CCDC170 Antibody, FITC conjugated
Biotin	CSB-PA815585LD01HU	CCDC170 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Plays a role in Golgi-associated microtubules organization and stabilization.

Gene References into Functions

Findings demonstrate that CCDC170 plays an essential role in Golgi-associated microtubules organization and stabilization, and implicate a mechanism for how perturbations in the CCDC170 gene may contribute to the hallmark changes in cell polarity and motility seen in breast cancer. PMID: 28687497
Data suggest that rs2046210 SNPs located in the region of C6ORF97 (CCDC170)-estrogen receptor alpha (ESR1) might have substantial roles not only in carcinogenesis but also in progression toward a more aggressive phenotype in breast cancer patients. PMID: 25370037
Our findings suggest that ESR1 and C6orf97 gene polymorphism is associated with fracture and vertebral fracture risk in Chinese postmenopausal women. PMID: 24481879
ESR1-CCDC170 rearrangements are found in an aggressive subset of estrogen receptor-positive breast cancers PMID: 25099679
Variation in rs3757318 of C6orf97 is associated with breast cancer risk. PMID: 25338983
SNPs associated with breast cancer differ for Asian, European, and African ancestry groups PMID: 20661439

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Subcellular Location

Golgi apparatus.

Database Links

HGNC: 21177

KEGG: hsa:80129

STRING: 9606.ENSP00000239374

UniGene: Hs.660044

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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