CDC42EP3 Antibody

Code CSB-PA006654
Size US$100
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  • Western Blot analysis of K562 cells using Cdc42EP3 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
CDC42EP3
Alternative Names
CDC42EP3 antibody; BORG2 antibody; CEP3Cdc42 effector protein 3 antibody; Binder of Rho GTPases 2 antibody; MSE55-related Cdc42-binding protein antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the N-terminal region of Human Cdc42EP3.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
Gene References into Functions
  1. Results provide evidence that Cdc42EP3 function in cancer-associated fibroblasts relies on tight regulation by Cdc42. PMID: 27248291
  2. The expression of CDC42EP3 mRNA was significantly increased by 19.7% in dorsal prefrontal cortex in patient with schizophrenia. PMID: 20385374
Subcellular Location
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Protein Families
BORG/CEP family
Tissue Specificity
Highly expressed in the heart and weakly in the brain.
Database Links

HGNC: 16943

OMIM: 606133

KEGG: hsa:10602

STRING: 9606.ENSP00000295324

UniGene: Hs.369574

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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