CDH16 Antibody

Code CSB-PA005041ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA005041ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CDH16 Polyclonal antibody
Uniprot No.
Target Names
CDH16
Alternative Names
CAD16_HUMAN antibody; Cadherin 16 antibody; Cadherin 16 KSP cadherin antibody; Cadherin kidney antibody; Cadherin-16 antibody; CDH 16 antibody; CDH16 antibody; Kidney cadherin antibody; Kidney specific cadherin antibody; Kidney-specific cadherin antibody; Ksp cadherin antibody; Ksp-cadherin antibody; PRO1340 antibody; UNQ695 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cadherin-16 protein (19-230AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Gene References into Functions
  1. Our study expands the clinical and allelic spectrum of known Retinal dystrophies genes, and reveals AGBL5, CDH16, and DNAJC17 as novel disease candidates. PMID: 26355662
  2. In thyroid carcinomas, as determined by quantitative RT-PCR, CDH16 expression decreases in papillary, follicular, and anaplastic thyroid carcinomas, and the decrease is more pronounced than that of CDH1. PMID: 22028439
  3. These results indicated that LIF induced multi-lineage differentiation of adult stem-like cells in kidney via cadherin 16. PMID: 15670782
  4. Ksp-cadherin expression downregulated inrenal cell carcinoma; this cell adhesion molecule may have role in tumour suppression PMID: 15886705
  5. Ksp-cad is a useful tumor type associated marker for distinguishing chromophobe renal cell carcinoma and renal oncocytoma from the wide range of nonintercalated cell-related adult renal epithelial neoplasms. PMID: 17895753
  6. The interaction of Ksp-cadherin with alpha B-crystallin is important for the connection of Ksp-cadherin to the cytoskeleton and thus for maintaining tissue integrity in the kidney. PMID: 18343407

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Kidney specific.
Database Links

HGNC: 1755

OMIM: 603118

KEGG: hsa:1014

STRING: 9606.ENSP00000299752

UniGene: Hs.513660

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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