CDH16 Antibody

Code CSB-PA001148
Size US$100
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  • Western Blot analysis of A549 cells using Cadherin-16 Polyclonal Antibody
  • Western Blot analysis of HuvEc cells using Cadherin-16 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
CDH16
Alternative Names
CAD16_HUMAN antibody; Cadherin 16 antibody; Cadherin 16 KSP cadherin antibody; Cadherin kidney antibody; Cadherin-16 antibody; CDH 16 antibody; CDH16 antibody; Kidney cadherin antibody; Kidney specific cadherin antibody; Kidney-specific cadherin antibody; Ksp cadherin antibody; Ksp-cadherin antibody; PRO1340 antibody; UNQ695 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of Human Cadherin-16.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Gene References into Functions
  1. Our study expands the clinical and allelic spectrum of known Retinal dystrophies genes, and reveals AGBL5, CDH16, and DNAJC17 as novel disease candidates. PMID: 26355662
  2. In thyroid carcinomas, as determined by quantitative RT-PCR, CDH16 expression decreases in papillary, follicular, and anaplastic thyroid carcinomas, and the decrease is more pronounced than that of CDH1. PMID: 22028439
  3. These results indicated that LIF induced multi-lineage differentiation of adult stem-like cells in kidney via cadherin 16. PMID: 15670782
  4. Ksp-cadherin expression downregulated inrenal cell carcinoma; this cell adhesion molecule may have role in tumour suppression PMID: 15886705
  5. Ksp-cad is a useful tumor type associated marker for distinguishing chromophobe renal cell carcinoma and renal oncocytoma from the wide range of nonintercalated cell-related adult renal epithelial neoplasms. PMID: 17895753
  6. The interaction of Ksp-cadherin with alpha B-crystallin is important for the connection of Ksp-cadherin to the cytoskeleton and thus for maintaining tissue integrity in the kidney. PMID: 18343407

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Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity
Kidney specific.
Database Links

HGNC: 1755

OMIM: 603118

KEGG: hsa:1014

STRING: 9606.ENSP00000299752

UniGene: Hs.513660

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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