CDK18 Antibody

Code CSB-PA017650GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CDK18
Alternative Names
Cdk18 antibody; CDK18_HUMAN antibody; Cell division protein kinase 18 antibody; Cyclin-dependent kinase 18 antibody; PCTAIRE 3 antibody; PCTAIRE antibody; PCTAIRE motif protein kinase 3 antibody; PCTAIRE protein kinase 3 antibody; PCTAIRE-motif protein kinase 3 antibody; PCTK 3 antibody; Serine/threonine-protein kinase PCTAIRE-3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PCTK3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May play a role in signal transduction cascades in terminally differentiated cells.
Gene References into Functions
  1. these data reveal a rate-limiting role for CDK18 in replication stress signalling and establish it as a novel regulator of genome integrity. PMID: 27382066
  2. Increased levels of PCTAIRE3 is associated with Alzheimer's disease. PMID: 26885753
  3. Expression of PCTAIRE 3a (474 amino acids) was evident throughout the brain and in the majority of tissues analyzed, while spliced isoform PCTAIRE 3b (504 amino acids) was limited to several subcortical nuclei of the basal gangli and the spinal cord. PMID: 15019984
  4. PCTAIRE 3 is aassociated kinase that modulates tau phosphorylation in Alzeheimer's disease. PMID: 16766195
Protein Families
Protein kinase superfamily, CMGC Ser/Thr protein kinase family, CDC2/CDKX subfamily
Tissue Specificity
Isoform 2 expression is limited to several subcortical nuclei of the basal gangli and the spinal cord. Isoform 1 is widely expressed.
Database Links

HGNC: 8751

OMIM: 169190

KEGG: hsa:5129

UniGene: Hs.445402

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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