CEACAM16 Antibody, HRP conjugated

Code CSB-PA005158LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CEACAM16 Polyclonal antibody
Uniprot No.
Target Names
CEACAM16
Alternative Names
CEACAM16 antibody; CEAL2Carcinoembryonic antigen-related cell adhesion molecule 16 antibody; Carcinoembryonic antigen-like 2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 16 protein (323-414AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.
Gene References into Functions
  1. Results confirm that CEACAM6 promoted cell proliferation mediated by cyclin D1/CDK4. PMID: 26497080
  2. Data indicate that a heterozygous missense mutation, c.505G>A (p.G169R) in exon 3 of the CEACAM16 gene (carcinoembryonic antigen-related cell adhesion molecule 16) was identified in autosomal dominant nonsyndromic hearing loss family. PMID: 25589040
  3. CEACAM16 can probably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and beta-tectorin and influences the physical properties of the tectorial membrane PMID: 22544735
  4. data identify CEACAM16 as an alpha-tectorin-interacting protein that concentrates at the point of attachment of the TM to the stereocilia and, when mutated, results in ADNSHL at the DFNA4 locus PMID: 21368133
Involvement in disease
Deafness, autosomal dominant, 4B (DFNA4B)
Subcellular Location
Secreted.
Protein Families
Immunoglobulin superfamily, CEA family
Database Links

HGNC: 31948

OMIM: 614591

KEGG: hsa:388551

STRING: 9606.ENSP00000385576

UniGene: Hs.456381

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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