Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 16 (CEACAM16)

Code CSB-YP005158HU
MSDS
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Source Yeast
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Code CSB-EP005158HU
MSDS
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Source E.coli
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Code CSB-EP005158HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP005158HU
MSDS
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Source Baculovirus
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Code CSB-MP005158HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
CEACAM16
Uniprot No.
Alternative Names
CEACAM16; CEAL2Carcinoembryonic antigen-related cell adhesion molecule 16; Carcinoembryonic antigen-like 2
Species
Homo sapiens (Human)
Expression Region
21-425
Target Protein Sequence
EISITLEPAQ PSEGDNVTLV VHGLSGELLA YSWYAGPTLS VSYLVASYIV STGDETPGPA HTGREAVRPD GSLDIQGILP RHSGTYILQT FNRQLQTEVG YGHVQVHEIL AQPTVLANST ALVERRDTLR LMCSSPSPTA EVRWFFNGGA LPVALRLGLS PDGRVLARHG IRREEAGAYQ CEVWNPVSVS RSEPINLTVY FGPERVAILQ DSTTRTGCTI KVDFNTSLTL WCVSRSCPEP EYVWTFNGQA LKNGQDHLNI SSMTAAQEGT YTCIAKNTKT LLSGSASVVV KLSAAAVATM IVPVPTKPTE GQDVTLTVQG YPKDLLVYAW YRGPASEPNR LLSQLPSGTW IAGPAHTGRE VGFPNCSLLV QKLNLTDTGR YTLKTVTVQG KTETLEVELQ VAPLG
Protein Length
Extracellular domain
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane.
Gene References into Functions
  1. Results confirm that CEACAM6 promoted cell proliferation mediated by cyclin D1/CDK4. PMID: 26497080
  2. Data indicate that a heterozygous missense mutation, c.505G>A (p.G169R) in exon 3 of the CEACAM16 gene (carcinoembryonic antigen-related cell adhesion molecule 16) was identified in autosomal dominant nonsyndromic hearing loss family. PMID: 25589040
  3. CEACAM16 can probably form higher order structures with other tectorial membrane proteins such as alpha-tectorin and beta-tectorin and influences the physical properties of the tectorial membrane PMID: 22544735
  4. data identify CEACAM16 as an alpha-tectorin-interacting protein that concentrates at the point of attachment of the TM to the stereocilia and, when mutated, results in ADNSHL at the DFNA4 locus PMID: 21368133
Involvement in disease
Deafness, autosomal dominant, 4B (DFNA4B)
Subcellular Location
Secreted.
Protein Families
Immunoglobulin superfamily, CEA family
Database Links

HGNC: 31948

OMIM: 614591

KEGG: hsa:388551

STRING: 9606.ENSP00000385576

UniGene: Hs.456381

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