CELF6 Antibody

Code CSB-PA002825GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CELF6
Alternative Names
6330569O16Rik antibody; Bruno like 6; RNA binding protein (Drosophila) antibody; bruno like 6; RNA binding protein antibody; Bruno like protein 6 antibody; Bruno-like protein 6 antibody; BRUNOL6 antibody; CELF-6 antibody; Celf6 antibody; CELF6_HUMAN antibody; CUG-BP- and ETR-3-like factor 6 antibody; CUGBP and ETR3 like factor 6 antibody; CUGBP Elav-like family member 6 antibody; RNA binding protein BRUNOL 6 antibody; RNA-binding protein BRUNOL-6 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human BRUNOL6
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA.
Gene References into Functions
  1. Analysis of common variants near the corresponding genes implicated the RNA binding protein CELF6 in autism risk PMID: 23407934
  2. CELF6 is a member of the CELF family of RNA-binding proteins that regulates muscle-specific splicing enhancer-dependent alternative splicing PMID: 14761971
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
CELF/BRUNOL family
Tissue Specificity
Expressed mainly in kidney, brain and testis and present in other tissues albeit at lower levels. Also expressed in fetal kidney.
Database Links

HGNC: 14059

OMIM: 612681

KEGG: hsa:60677

STRING: 9606.ENSP00000287202

UniGene: Hs.348342

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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