CEP170 Antibody

Code CSB-PA001570
Size US$119
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  • Western Blot analysis of AD293 cells using CEP170 Polyclonal Antibody
  • Western Blot analysis of MCF7 PC-3 Hela cells using CEP170 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
CEP170
Alternative Names
CEP170 antibody; FAM68A antibody; KAB antibody; KIAA0470Centrosomal protein of 170 kDa antibody; Cep170 antibody; KARP-1-binding protein antibody; KARP1-binding protein antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of Human CEP170.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Plays a role in microtubule organization. Required for centriole subdistal appendage assembly.
Gene References into Functions
  1. Data suggest that CDK5RAP2 and CEP170 both interact with microtubule nucleation-promoting region of AKAP350A; CEP68 interacts with distal C-terminal region of AKAP350A; AKAP350A spans the bridge between centrioles. (CDK5RAP2 = CDK5 regulatory subunit associated protein 2; CEP170 = centrosomal protein 170kDa; AKAP350A = A kinase (PRKA) anchor protein (yotiao) 9; CEP68 = centrosomal protein 68kDa) PMID: 29054927
  2. Data indicate that Cep170 association with the C-terminus of Kif2b enhances localization of Kif2b to the spindle. PMID: 23087211
  3. Cep170 interacts with Polo-like kinase 1 in mature centrioles. PMID: 15616186
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle.
Protein Families
CEP170 family
Database Links

HGNC: 28920

OMIM: 613023

KEGG: hsa:9859

STRING: 9606.ENSP00000355500

UniGene: Hs.533635

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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