CEP89 Antibody

Code CSB-PA853505LA01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CEP89 Polyclonal antibody
Uniprot No.
Target Names
CEP89
Alternative Names
CCDC123 antibody; Centrosomal protein 89 kDa antibody; Centrosomal protein of 89 kDa antibody; cep89 antibody; CEP89_HUMAN antibody; Coiled-coil domain-containing protein 123 antibody; Coiled-coil domain-containing protein 123; mitochondrial antibody; FLJ14640 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Centrosomal protein of 89 kDa protein (25-235AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CEP89 Antibody (Product code: CSB-PA853505LA01HU) is Non-conjugated. For CEP89 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA853505LB01HU CEP89 Antibody, HRP conjugated ELISA
FITC CSB-PA853505LC01HU CEP89 Antibody, FITC conjugated
Biotin CSB-PA853505LD01HU CEP89 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for ciliogenesis. Also plays a role in mitochondrial metabolism where it may modulate complex IV activity.
Gene References into Functions
  1. CEP89 proteins play an important role in mitochondrial metabolism, especially complex IV activity, and are required for neuronal and cognitive function across evolution. PMID: 23575228
Involvement in disease
Homozygous deletion comprising CEP89 and SLC7A9 genes has been reported in a patient with isolated complex IV deficiency, intellectual disability and multisystemic problems that include cystinuria, cataract, broad based walking pattern and deafness.
Subcellular Location
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Mitochondrion intermembrane space. Note=Localizes to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane.
Database Links

HGNC: 25907

OMIM: 615470

KEGG: hsa:84902

STRING: 9606.ENSP00000306105

UniGene: Hs.599703

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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