CHCHD6 Antibody

Code CSB-PA005321GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CHCHD6
Alternative Names
CHCH6_HUMAN antibody; Chchd6 antibody; CHCM1 antibody; Coiled coil helix cristae morphology 1 antibody; Coiled coil helix cristae morphology protein 1 antibody; Coiled-coil-helix-coiled-coil-helix domain-containing protein 6 antibody; Coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial antibody; Mic25 antibody; MICOS complex subunit MIC25 antibody; PPP1R23 antibody; Protein phosphatase 1 regulatory subunit 23 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Human CHCHD6
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
Gene References into Functions
  1. mitochondria exhibited lower cristae density in CHCHD6-knockout cells. CHCHD6 directly interacted with Sam50. PMID: 26530328
  2. CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology. PMID: 22228767
  3. anti-mitofilin mAb immunocaptures its target protein in association with six other proteins, metaxins 1 and 2, SAM50, CHCHD3, CHCHD6 and DnaJC11, respectively PMID: 17624330
Subcellular Location
Mitochondrion inner membrane; Lipid-anchor. Mitochondrion.
Protein Families
MICOS complex subunit Mic19 family, Metazoan Mic25 subfamily
Database Links

HGNC: 28184

OMIM: 615634

KEGG: hsa:84303

STRING: 9606.ENSP00000290913

UniGene: Hs.518119

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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