CHRNA10 Antibody

Datasheet

Code	CSB-PA005387GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q9GZZ6

Target Names

CHRNA10

Alternative Names

Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit antibody; ACH10_HUMAN antibody; Alpha 10 nAChR antibody; Cholinergic receptor nicotinic alpha 10 antibody; Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10 antibody; Cholinergic receptor, nicotinic, alpha polypeptide 10 antibody; CHRNA 10 antibody; CHRNA10 antibody; NACHR alpha 10 antibody; NACHR alpha-10 antibody; NACHRA10 antibody; Neuronal acetylcholine receptor protein subunit alpha 10 antibody; Neuronal acetylcholine receptor subunit alpha-10 antibody; Nicotinic acetylcholine receptor subunit alpha 10 antibody; Nicotinic acetylcholine receptor subunit alpha-10 antibody; OTTHUMP00000013620 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human CHRNA10

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

Gene References into Functions

A two order of magnitude species difference is reported in potency of alpha-conotoxin RgIA for rat versus human alpha9alpha10 nAChR. PMID: 22774872
CHRNA10 may have a role in "dizziness" in response to tobacco PMID: 19760673

Subcellular Location

Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Protein Families

Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Alpha-10/CHRNA10 sub-subfamily

Tissue Specificity

Expressed in inner-ear tissue, tonsil, immortalized B-cells, cultured T-cells and peripheral blood lymphocytes.

Database Links

HGNC: 13800

OMIM: 606372

KEGG: hsa:57053

STRING: 9606.ENSP00000250699

UniGene: Hs.732806

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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