CIDEB Antibody

Code CSB-PA12869A0Rb
Size US$166
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  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA12869A0Rb at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human lung tissue using CSB-PA12869A0Rb at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CIDEB Polyclonal antibody
Uniprot No.
Target Names
CIDEB
Alternative Names
Cell death activator CIDE B antibody; Cell death activator CIDE-B antibody; Cell death inducing DFFA like effector B antibody; Cell death-inducing DFFA-like effector B antibody; CIDEB antibody; CIDEB_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Cell death activator CIDE-B protein (80-145AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CIDEB Antibody (Product code: CSB-PA12869A0Rb) is Non-conjugated. For CIDEB Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA12869B0Rb CIDEB Antibody, HRP conjugated ELISA
FITC CSB-PA12869C0Rb CIDEB Antibody, FITC conjugated
Biotin CSB-PA12869D0Rb CIDEB Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Activates apoptosis.; (Microbial infection) Involved in Hepatatis C virus (HCV) assembly and required for HCV entry into hepatocytes.
Gene References into Functions
  1. High Cideb expression is associated with Ulcerative Colitis. PMID: 28719542
  2. CIDEB interacts with the HCV NS5A protein, and the N terminus of CIDEB and the domain I of NS5A are involved in this interaction. PMID: 27282740
  3. these data revealed that Cideb plays an important role in controlling intestinal chylomicron lipidation. PMID: 24831470
  4. this study shows that C5a signaling induces apoptosis in brain vascular endothelial cells in experimental lupus through activation of CIDEB PMID: 27213693
  5. CIDEB downregulation may contribute to HCV-induced hepatic steatosis PMID: 26865724
  6. CIDEB can act as an anti-HCV host factor and contribute to altered triglyceride homeostasis. PMID: 24980280
  7. Authors found CIDEB to be an essential cofactor for hepatitis C virus entry into hepatocytes. PMID: 24829338
  8. this work highlights CIDEB's role in lipid droplet (LD) fusion, and presents a new model system to study the PGC-1alpha/CIDEB pathway's role in LD dynamics and the VLDL pathway. PMID: 24161736
  9. CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma. PMID: 23475172
  10. A novel mechanism for the cell-specific transcription of the human CIDE-B gene, which involves epigenetic and genetic control at separate respective promoters is reported. PMID: 16248853

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Tissue Specificity
Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen.
Database Links

HGNC: 1977

OMIM: 604441

KEGG: hsa:27141

STRING: 9606.ENSP00000258807

UniGene: Hs.642693

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