CMTM5 Antibody

1. Overexpression of CMTM5 attenuated vascular endothelial cells migration and proliferation. PMID: 28457985
2. results indicate that CMTM5 is down-regulated in prostate cancer and exhibit tumor suppressor activities in androgen-independent prostate cancer cells PMID: 25387568
3. In the OSCC cell lines CAL27 and GNM, the ectopic expression of CMTM5-v1 strongly inhibited cell proliferation and migration and induced apoptosis. PMID: 24721428
4. The reduced expression of CMTM5 correlates significantly with poorly differentiated ovarian cancer and high preoperative CA125 level. PMID: 21841490
5. Data suggest that CMTM5 may be involved in the pathomechanism of myeloid leukemias. PMID: 21168207
6. The expression level of cmtm5 gene is abnormally lower in the bone marrow cells from the multiple myeloma patients, and are associated with ISS stages. PMID: 20416169
7. HER2 was up regulated in prostate cancer epithelium while CMTM5 was down regulated. Overexpression of CMTM5 in PC3 cells could lower the HER2 and Cyclin D1 protein level. PMID: 20721248
8. CMTM5-v1 might be secreted via a different vesicle-mediated secretory pathway, which will be helpful for the studies of vesicle-mediated secretion and MARVEL domain-containing proteins. PMID: 20356458
9. CMTM5 exhibits tumor suppressor activities, but with frequent epigenetic inactivation in carcinoma cell lines PMID: 17908965
10. These findings verify that CMTM5-v1 inhibits the growth of CC cell lines via inducing apoptosis. PMID: 19124004
11. CMTM5 may play a role in the pancreatic cancer. PMID: 19577543

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HGNC: 19176

OMIM: 607888

KEGG: hsa:116173

STRING: 9606.ENSP00000352270

UniGene: Hs.99272