CNIH3 Antibody

Code CSB-PA005650GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CNIH3
Alternative Names
CNIH3; Protein cornichon homolog 3; CNIH-3; Cornichon family AMPA receptor auxiliary protein 3
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CNIH3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization.
Gene References into Functions
  1. Study's convergent findings in humans and mice support CNIH3 involvement in the pathophysiology of opioid dependence, complementing prior studies implicating the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate system PMID: 26239289
  2. Significant upregulation of CNIH-3 mRNA expression was found in schizophrenia. PMID: 23103966
Subcellular Location
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
Protein Families
Cornichon family
Tissue Specificity
Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia (postmortem brain study).
Database Links

HGNC: 26802

KEGG: hsa:149111

STRING: 9606.ENSP00000272133

UniGene: Hs.731723

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