CNN3 Antibody

Datasheet

Code	CSB-PA005657LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA005657LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA005657LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA005657LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Western Blot Positive WB detected in: Mouse liver tissue All lanes: CNN3 antibody at 3.4μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 37, 32 kDa Observed band size: 37 kDa
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CNN3 Polyclonal antibody

Uniprot No.

Q15417

Target Names

CNN3

Alternative Names

Acidic calponin 3 antibody; acidic isoform antibody; Calponin 3 acidic antibody; Calponin 3 antibody; Calponin acidic antibody; Calponin acidic isoform antibody; Calponin antibody; Calponin-3 antibody; Calponin3 antibody; CNN 3 antibody; Cnn3 antibody; CNN3_HUMAN antibody; dJ639P13.2.2 antibody; OTTHUMP00000012470 antibody; OTTHUMP00000012471 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Calponin-3 protein (2-329AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CNN3 Antibody (Product code: CSB-PA005657LA01HU) is Non-conjugated. For CNN3 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA005657LB01HU	CNN3 Antibody, HRP conjugated	ELISA
FITC	CSB-PA005657LC01HU	CNN3 Antibody, FITC conjugated
Biotin	CSB-PA005657LD01HU	CNN3 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.

Gene References into Functions

These results reveal the importance of the MEKK1-calponin-3 signaling pathway to cell contractility. PMID: 27528401
overexpressed CNN3 during sonic vibration increases expression of glutamate receptors and promotes functional neural differentiation of human umbilical cords-mesenchymal stem cells. PMID: 26175098
CNN3 as a new pro-invasive protein in trophoblast cells that is induced under low oxygen conditions. PMID: 25050546
Participates in actin stress fiber remodeling PMID: 23545751
The mRNA and protein level of calponin-3 were increase expression in brain in patiens with epilepsy. PMID: 22119193
Results indicate that CNN3 regulates actin cytoskeleton rearrangement which is required for the plasma membranes of trophoblasts to become fusion competent. PMID: 20861310
These results suggest a role of calponin 3 in the regulation of Bone morphogenetic proteins -dependent cellular responses. PMID: 17825283
Gene rearrangements of CNN3 is associated with mucosa-associated lymphoid tissue lymphoma. PMID: 18927281

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Protein Families

Calponin family

Tissue Specificity

Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.

Database Links

HGNC: 2157

OMIM: 602374

KEGG: hsa:1266

STRING: 9606.ENSP00000359225

UniGene: Hs.483454

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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