CNTN6 Antibody

Code CSB-PA891801LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: HepG2 whole cell lysate
    All lanes: CNTN6 antibody at 2.7µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 114 kDa
    Observed band size: 114 kDa

  • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA891801LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CNTN6 Polyclonal antibody
Uniprot No.
Target Names
CNTN6
Alternative Names
CNTN 6 antibody; CNTN6 antibody; CNTN6_HUMAN antibody; Contactin 6 precursor antibody; Contactin-6 antibody; Contactin6 antibody; hNB 3 antibody; hNB-3 antibody; hNB3 antibody; MGC133256 antibody; NB 3 antibody; NB3 antibody; Neural adhesion molecule antibody; Neural recognition molecule NB 3 antibody; Neural recognition molecule NB-3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Contactin-6 protein (706-812AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CNTN6 Antibody (Product code: CSB-PA891801LA01HU) is Non-conjugated. For CNTN6 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA891801LB01HU CNTN6 Antibody, HRP conjugated ELISA
FITC CSB-PA891801LC01HU CNTN6 Antibody, FITC conjugated
Biotin CSB-PA891801LD01HU CNTN6 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Involved in motor coordination.
Gene References into Functions
  1. Clinical investigations of the patients carrying CNTN5 or CNTN6 variants showed that they were hypersensitive to sounds (a condition called hyperacusis) and displayed changes in wave latency within the auditory pathway. PMID: 27166760
  2. CNTN6 copy number variants (duplications) were associated with increased risk of Tourette syndrome. PMID: 28641109
Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Protein Families
Immunoglobulin superfamily, Contactin family
Tissue Specificity
Expressed in nervous system. Highly expressed in cerebellum. Expressed at intermediate level in thalamus, subthalamic nucleus. Weakly expressed in corpus callosum, caudate nucleus and spinal cord.
Database Links

HGNC: 2176

OMIM: 607220

KEGG: hsa:27255

STRING: 9606.ENSP00000341882

UniGene: Hs.387300

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