COG5 Antibody

Code CSB-PA890771ESR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA890771ESR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA890771ESR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) COG5 Polyclonal antibody
Uniprot No.
Target Names
COG5
Alternative Names
COG5 antibody; GOLTC1 antibody; GTC90Conserved oligomeric Golgi complex subunit 5 antibody; COG complex subunit 5 antibody; 13S Golgi transport complex 90 kDa subunit antibody; GTC-90 antibody; Component of oligomeric Golgi complex 5 antibody; Golgi transport complex 1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Conserved oligomeric Golgi complex subunit 5 protein (1-260AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for normal Golgi function.
Gene References into Functions
  1. Targeted silencing of components of lobe B of the COG complex, namely COG5, COG6, COG7 and COG8, inhibited HIV-1 replication PMID: 25179963
  2. Cog5-Cog7 crystal structure reveals interactions essential for the function of a multisubunit tethering complex. PMID: 25331899
  3. In conclusion, we find that GDF5, but not COG5 or MCF2L, influence the extent of radiographic damage in knee osteoarthritis PMID: 22615457
  4. Report on a uterine leiomyoma with a novel HMGA2 fusion gene in a 44-year-old woman. PMID: 20804914
  5. Sec34 is implicated in traffic from the endoplasmic reticulum to the Golgi and exists in a complex with GTC-90 and ldlBp PMID: 11929878
  6. COG5- and COG7 subunits play distinctive roles in controlling Golgi structure and function PMID: 16051600

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Involvement in disease
Congenital disorder of glycosylation 2I (CDG2I)
Subcellular Location
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein.
Protein Families
COG5 family
Database Links

HGNC: 14857

OMIM: 606821

KEGG: hsa:10466

STRING: 9606.ENSP00000297135

UniGene: Hs.239631

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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