COL5A3 Antibody

Code CSB-PA034900
Size US$297
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  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using Collagen V α3 antibody.
  • Immunofluorescence analysis of HeLa cells, using Collagen V α3 antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) COL5A3 Polyclonal antibody
Uniprot No.
Target Names
COL5A3
Alternative Names
COL5A3Collagen alpha-3(V) chain antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Synthesized peptide derived from internal of Human Collagen V α3.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,IHC,IF
Recommended Dilution
Application Recommended Dilution
IHC 1:50-1:100
IF 1:100-1:500
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin.
Gene References into Functions
  1. analysis of processing of the Pro-alpha1(V)Pro-alpha2(V)Pro-alpha3(V) procollagen heterotrimer PMID: 15136578
  2. CBF/NF-Y and two repressors regulate the core promoter of the human pro-alpha3(V) collagen gene PMID: 15316020
  3. Absence of obvious disease-causing mutations and null alleles in a cohort of 13 patients with h-EDS is consistent with exclusion of COL5A3 as a candidate gene for this disease. PMID: 19012342
Subcellular Location
Secreted, extracellular space, extracellular matrix.
Protein Families
Fibrillar collagen family
Database Links

HGNC: 14864

OMIM: 120216

KEGG: hsa:50509

STRING: 9606.ENSP00000264828

UniGene: Hs.235368

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