COPS7A Antibody

Code CSB-PA880068HA01HU
Size US$166
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  • Western blot
    All lanes: COP9 signalosome complex subunit 7a antibody at 2μg/ml + Mouse brain tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 30 kDa
    Observed band size: 30 kDa

  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA880068HA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA880068HA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) COPS7A Polyclonal antibody
Uniprot No.
Target Names
COPS7A
Alternative Names
COP9 complex subunit 7a antibody; COP9 constitutive photomorphogenic homolog subunit 7A antibody; COP9 signalosome complex subunit 7a antibody; COP9 signalosome subunit 7A antibody; COPS7A antibody; CSN7A antibody; CSN7A_HUMAN antibody; Dermal papilla derived protein 10 antibody; Dermal papilla-derived protein 10 antibody; DERP10 antibody; JAB1 containing signalosome subunit 7a antibody; JAB1-containing signalosome subunit 7a antibody; SGN7a antibody; Signalosome subunit 7a antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human COP9 signalosome complex subunit 7a protein (2-275AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The COPS7A Antibody (Product code: CSB-PA880068HA01HU) is Non-conjugated. For COPS7A Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA880068HB01HU COPS7A Antibody, HRP conjugated ELISA
FITC CSB-PA880068HC01HU COPS7A Antibody, FITC conjugated
Biotin CSB-PA880068HD01HU COPS7A Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
CSN7/EIF3M family, CSN7 subfamily
Tissue Specificity
Widely expressed. Expressed at high level in brain, heart and skeletal muscle.
Database Links

HGNC: 16758

OMIM: 616009

KEGG: hsa:50813

STRING: 9606.ENSP00000229251

UniGene: Hs.530823

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