COQ7 Antibody

Code CSB-PA005806GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
COQ7
Alternative Names
COQ7 antibody; 5-demethoxyubiquinone hydroxylase antibody; mitochondrial antibody; DMQ hydroxylase antibody; EC 1.14.13.- antibody; Timing protein clk-1 homolog antibody; Ubiquinone biosynthesis monooxygenase COQ7 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human COQ7
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
Gene References into Functions
  1. cCOQ7 COQ7 vCOQ7 PMID: 28409910
  2. Mitochondrial COQ9 is a lipid-binding protein that associates with COQ7 to enable coenzyme Q biosynthesis. PMID: 25339443
  3. action of clioquinol on several age-dependent neurodegenerative diseases with distinct etiologies might result from a slowing down of the aging process through action of the drug on CLK-1. PMID: 18927074
  4. The siRNA-mediated knock down leads to an increase in cytoplasmic superoxide dismutase (SOD1) mRNA levels and activity PMID: 19135146
Involvement in disease
Coenzyme Q10 deficiency, primary, 8 (COQ10D8)
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Protein Families
COQ7 family
Tissue Specificity
Expressed dominantly in heart and skeletal muscle.
Database Links

HGNC: 2244

OMIM: 601683

KEGG: hsa:10229

STRING: 9606.ENSP00000322316

UniGene: Hs.157113

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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