CPLX3 Antibody

Code CSB-PA005895GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
CPLX3
Alternative Names
CPLX3 antibody; Nbla11589Complexin-3 antibody; Complexin III antibody; CPX III antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human CPLX3
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release.
Gene References into Functions
  1. CPX acts sequentially on assembling SNAREpins, first facilitating zippering by nearly doubling the distance at which v- and t-SNAREs can engage and then clamping them into a half-zippered fusion-incompetent state. PMID: 21785413
Subcellular Location
Cell junction, synapse. Cell membrane; Lipid-anchor.
Protein Families
Complexin/synaphin family
Database Links

HGNC: 27652

OMIM: 609585

KEGG: hsa:594855

STRING: 9606.ENSP00000378464

UniGene: Hs.187694

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