CPO Antibody

Datasheet

Code	CSB-PA005909LA01HU
Size	US$166
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Image	Immunofluorescence staining of HepG2 cells with CSB-PA005909LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CPO Polyclonal antibody

Uniprot No.

Q8IVL8

Target Names

CPO

Alternative Names

Carboxypeptidase O antibody; CBPO_HUMAN antibody; CPO antibody; Metallocarboxypeptidase C antibody; Metallocarboxypeptidase O antibody; MGC138281 antibody; MGC138283 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Carboxypeptidase O protein (21-101AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CPO Antibody (Product code: CSB-PA005909LA01HU) is Non-conjugated. For CPO Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA005909LB01HU	CPO Antibody, HRP conjugated	ELISA
FITC	CSB-PA005909LC01HU	CPO Antibody, FITC conjugated
Biotin	CSB-PA005909LD01HU	CPO Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Carboxypeptidase which preferentially cleaves C-terminal acidic residues from peptides and proteins. Can also cleave C-terminal hydrophobic amino acids, with a preference for small residues over large residues.

Gene References into Functions

hCPO can also trim C-t extensions of proteins, such as epidermal growth factor, suggesting a role in the maturation and degradation of growth factors and bioactive peptides. PMID: 29636417
CPO cleaves acidic amino acids from dietary proteins and peptides, thus complementing the actions of well known digestive carboxypeptidases CPA and CPB. PMID: 21921028

Subcellular Location

Apical cell membrane; Lipid-anchor, GPI-anchor.

Protein Families

Peptidase M14 family

Tissue Specificity

Detected in enterocytes of the ileum.

Database Links

HGNC: 21011

OMIM: 609563

KEGG: hsa:130749

STRING: 9606.ENSP00000272852

UniGene: Hs.684103

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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