CRYAA Antibody

Datasheet

Code	CSB-PA006007LA01HU
Size	US$166
	Order now
Image	Immunofluorescence staining of HepG2 cells with CSB-PA006007LA01HU at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
The Latest Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CRYAA Polyclonal antibody

Uniprot No.

P02489

Target Names

CRYAA

Alternative Names

Acry 1 antibody; Alpha crystallin A chain antibody; Alpha-crystallin A chain antibody; CRYA 1 antibody; CRYA1 antibody; CRYAA antibody; CRYAA_HUMAN antibody; Crystallin alpha 1 antibody; Crystallin alpha A antibody; Heat shock protein beta 4 antibody; Heat shock protein beta-4 antibody; HSPB 4 antibody; HspB4 antibody; short form antibody; Zonular Central Nuclear Cataract antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Alpha-crystallin A chain protein (98-173AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CRYAA Antibody (Product code: CSB-PA006007LA01HU) is Non-conjugated. For CRYAA Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA006007LB01HU	CRYAA Antibody, HRP conjugated	ELISA
FITC	CSB-PA006007LC01HU	CRYAA Antibody, FITC conjugated
Biotin	CSB-PA006007LD01HU	CRYAA Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, IF

Recommended Dilution

Application	Recommended Dilution
IF	1:50-1:200

Protocols

ELISA Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Contributes to the transparency and refractive index of the lens. In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.

Gene References into Functions

CRISPR/Cas9-mediated mutation of the alphaA-crystallin gene in rabbits recapitulates phenotypes of congenital cataracts, microphthalmia, obscurity, and early atrophy of the lens, and failed differentiation of lens fibers. PMID: 28475701

Involvement in disease

Cataract 9, multiple types (CTRCT9)

Subcellular Location

Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.

Protein Families

Small heat shock protein (HSP20) family

Tissue Specificity

Expressed in the eye lens (at protein level).

Database Links

HGNC: 2388

OMIM: 123580

KEGG: hsa:102724652

STRING: 9606.ENSP00000291554

UniGene: Hs.184085

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address