CRYBA4 Antibody

Code CSB-PA006011LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Mouse heart tissue
    All lanes: CRYBA4 antibody at 3µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 23 kDa
    Observed band size: 23 kDa

  • Immunohistochemistry analysis of human eye tissue using CSB-PA006011LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CRYBA4 Polyclonal antibody
Uniprot No.
Target Names
CRYBA4
Alternative Names
Beta A4 crystallin antibody; Beta crystallin A4 antibody; Beta-A4 crystallin antibody; Beta-crystallin A4 antibody; CRBA4_HUMAN antibody; CRYBA4 antibody; Crystallin beta A4 antibody; Crystallin; beta polypeptide A4 antibody; CTRCT23 antibody; Eye lens structural protein antibody; MCOPCT4 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Beta-crystallin A4 protein (2-196AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The CRYBA4 Antibody (Product code: CSB-PA006011LA01HU) is Non-conjugated. For CRYBA4 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA006011LB01HU CRYBA4 Antibody, HRP conjugated ELISA
FITC CSB-PA006011LC01HU CRYBA4 Antibody, FITC conjugated
Biotin CSB-PA006011LD01HU CRYBA4 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Crystallins are the dominant structural components of the vertebrate eye lens.
Gene References into Functions
  1. CRYBA4 duplication and CRYBB1 partial duplication identified in a family with autosomal dominant congenital cataract. PMID: 28272538
  2. rs2009066 located in the crystallin beta A4 (CRYBA4) gene was identified to be the most significantly associated with high myopia. PMID: 22792142
  3. Novel missense mutation in CRYBA4 expands mutation spectrum of CRYBA4 and provides useful information to study of molecular pathogenesis of cataract and microcornea. PMID: 20577656
  4. first report linking mutations in CRYBA4 to cataractogenesis and microphthalmia PMID: 16960806
Involvement in disease
Cataract 23, multiple types (CTRCT23)
Protein Families
Beta/gamma-crystallin family
Database Links

HGNC: 2396

OMIM: 123631

KEGG: hsa:1413

STRING: 9606.ENSP00000346805

UniGene: Hs.57690

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