CST1 Antibody

1. Results revealed that CST1 expression was upregulated in colon cancer (CC) compared with normal tissues and contributed to CC cell proliferation. PMID: 29845224
2. High CST1 expression is negatively correlated with survival of breast cancer patients. CST1 promotes cell proliferation, clone formation, and metastasis in breast cancer cells. CST1 is a novel potential prognostic biomarker and therapeutic target for breast cancer. PMID: 28523467
3. this results identified cystatin 1 as a biomarker in patients with seasonal allergic rhinitis PMID: 28633877
4. These results indicate that CST1-mediated extracellular CatB activity enhances tumor development by preventing cellular senescence. PMID: 28383558
5. interactions of human family 1 & 2 cystatins with cathepsin L1 PMID: 27764212
6. high expression of Cystatin SN is a significant prognostic indicator of a higher rate of recurrence, metastatic risk, and poor survival in patients with surgically resected NSCLCs. PMID: 25648368
7. In conclusion, our data suggest that CST1 might contribute to the proliferation of pancreatic cancer cells and could be a potential biomarker for the early detection of pancreatic cancer. PMID: 25577248
8. CST1 may contribute to inactivation of protease allergens and help re-establish homeostasis of the nasal membranes. PMID: 23950865
9. CST1 expression at both the messenger RNA and protein levels was barely detected in control cells, which included early passage proliferating, quiescent, or immortal human fibroblasts PMID: 21636832
10. Murine monoclonal antibodies were made which can distinguish between CST1 and CST2. PMID: 15829315
11. CST1 might be highly involved in gastric tumorigenesis and regulate the proteolytic activity of cysteine proteases. PMID: 19463800
12. Identification of Cystatin SN as a novel tumor marker for colorectal cancer. PMID: 19513549

Show More

Hide All

HGNC: 2473

OMIM: 123855

KEGG: hsa:1469

STRING: 9606.ENSP00000305731

UniGene: Hs.123114