CYB5R4 Antibody

Datasheet

Code	CSB-PA006321GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q7L1T6

Target Names

CYB5R4

Alternative Names

b5+b5R antibody; b5b5r antibody; C79736 antibody; cb5/cb5R antibody; Cb5cb5r antibody; Cyb5r4 antibody; Cytochrome b type NAD(P)H oxidoreductase antibody; Cytochrome b5 reductase 4 antibody; dJ676J13.1 antibody; Flavohemoprotein b5+b5R antibody; Flavohemoprotein b5/b5R antibody; N terminal cytochrome b5 and cytochrome b5 oxidoreductase domain containing protein antibody; N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein antibody; NADPH cytochrome B5 oxidoreductase antibody; NB5R4_HUMAN antibody; NCB5OR antibody; RP4 676J13.1 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human CYB5R4

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

NADH-cytochrome b5 reductase involved in endoplasmic reticulum stress response pathway. Plays a critical role in protecting pancreatic beta-cells against oxidant stress, possibly by protecting the cell from excess buildup of reactive oxygen species (ROS). Reduces a variety of substrates in vitro, such as cytochrome c, feericyanide and methemoglobin.

Gene References into Functions

Cytosolic localization of NADH cytochrome b oxidoreductase PMID: 26878259
data provide first evidence for natural mutations in NCB5OR gene resulting in decreased protein levels and hence having potential implications in human pathology. PMID: 23523930
Mutation in cytochrome b5 reductase is associated with developmental delay and severe neurological problems. PMID: 22627575
Study of the individual cytochrome b5 and cytochrome b5 reductase domains of Ncb5or reveals a unique heme pocket and a possible role of the CS domain. PMID: 20630863
NCB5OR is a novel soluble NAD(P)H reductase localized in the endoplasmic reticulum PMID: 15131110
Variaation in the coding region is not a major contributor in the pathogenesis of nonautoimmune diabetes. PMID: 15504981

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Subcellular Location

Endoplasmic reticulum. Note=Soluble protein.

Protein Families

Flavoprotein pyridine nucleotide cytochrome reductase family

Tissue Specificity

Widely expressed.

Database Links

HGNC: 20147

OMIM: 608343

KEGG: hsa:51167

STRING: 9606.ENSP00000358695

UniGene: Hs.5741

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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