CYP3A43 Antibody

Code CSB-PA862059ESR1HU
Size US$166
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  • Western blot
    All lanes: CYP3A43 antibody at 3.25 μg/ml
    Lane 1: Mouse liver tissue
    Lane 2: Mouse skeletal muscle tissue
    Lane 3: 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 58, 49, 29, 45 kDa
    Observed band size: 58, 45 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CYP3A43 Polyclonal antibody
Uniprot No.
Target Names
CYP3A43
Alternative Names
CYP3A43Cytochrome P450 3A43 antibody; EC 1.14.14.1 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Cytochrome P450 3A43 protein (244-503AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Exhibits low testosterone 6-beta-hydroxylase activity.
Gene References into Functions
  1. Mutations in CYP3A43 gene is associated with prostate cancer. PMID: 26585945
  2. This review support the notion that the SNP CYP3A43this may play a role in antipsychotic response. PMID: 25150845
  3. CYP3A43 rs472660 is not likely to be a major contributor towards variability in systemic OLA exposure among White patients PMID: 24595013
  4. No differences in genotype frequencies between cases and controls were observed, indicating that CYP3A43_74_delA is not associated with breast cancer risk. PMID: 20715157
  5. Finds CYP3A43-Pro(340)Ala polymorphism prevalence differs by race and contributes to prostate cancer risk in African Americans. PMID: 15894682
  6. analysis of the restriction fragment length polymorphism CYP3A43 gene c1047 > T in europeoid residents of West Siberia PMID: 16848237

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Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein Families
Cytochrome P450 family
Tissue Specificity
Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle.
Database Links

HGNC: 17450

OMIM: 606534

KEGG: hsa:64816

STRING: 9606.ENSP00000222382

UniGene: Hs.306220

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