CYP3A43 Antibody

Code CSB-PA862059ESR1HU
Size US$166
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  • Western blot
    All lanes: CYP3A43 antibody at 3.25 μg/ml
    Lane 1: Mouse liver tissue
    Lane 2: Mouse skeletal muscle tissue
    Lane 3: 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 58, 49, 29, 45 kDa
    Observed band size: 58, 45 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CYP3A43 Polyclonal antibody
Uniprot No.
Target Names
CYP3A43
Alternative Names
CYP3A43Cytochrome P450 3A43 antibody; EC 1.14.14.1 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Cytochrome P450 3A43 protein (244-503AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Exhibits low testosterone 6-beta-hydroxylase activity.
Gene References into Functions
  1. Mutations in CYP3A43 gene is associated with prostate cancer. PMID: 26585945
  2. This review support the notion that the SNP CYP3A43this may play a role in antipsychotic response. PMID: 25150845
  3. CYP3A43 rs472660 is not likely to be a major contributor towards variability in systemic OLA exposure among White patients PMID: 24595013
  4. No differences in genotype frequencies between cases and controls were observed, indicating that CYP3A43_74_delA is not associated with breast cancer risk. PMID: 20715157
  5. Finds CYP3A43-Pro(340)Ala polymorphism prevalence differs by race and contributes to prostate cancer risk in African Americans. PMID: 15894682
  6. analysis of the restriction fragment length polymorphism CYP3A43 gene c1047 > T in europeoid residents of West Siberia PMID: 16848237

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Subcellular Location
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Protein Families
Cytochrome P450 family
Tissue Specificity
Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle.
Database Links

HGNC: 17450

OMIM: 606534

KEGG: hsa:64816

STRING: 9606.ENSP00000222382

UniGene: Hs.306220

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