CYP4B1 Antibody

Datasheet

Code	CSB-PA006448ESR1HU
Size	US$166
	Order now
Image	Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA006448ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA006448ESR1HU at dilution of 1:100
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CYP4B1 Polyclonal antibody

Uniprot No.

P13584

Target Names

CYP4B1

Alternative Names

CP4B1_HUMAN antibody; CYP4B1 antibody; CYPIVB1 antibody; Cytochrome P450 4B1 antibody; Cytochrome P450 family 4 subfamily B polypeptide 1 antibody; Cytochrome P450 subfamily IVB polypeptide 1 antibody; Cytochrome P450-HP antibody; Microsomal monooxygenase antibody; P450HP antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Cytochrome P450 4B1 protein (30-250AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.

Gene References into Functions

the Ser207 insertion does not rescue the P450 functional activity of human CYP4B1 that has been lost during evolution. PMID: 26355749
A proline residue in the meander region at position 427 in human CYP4B1 and 422 in rabbit CYP4B1 is important for protein stability and rescues the 4-ipomeanol bioactivation. PMID: 25247810
polymorphism in humans: evidence for a non-functional allelic variant PMID: 12142726
CYP4B1 is a senescene-associated gene in normal human oral keratinocytes. PMID: 12837283
Results demostrated an increased risk of bladder cancer associated with the CYP4B1*1/*2 and *2/*2 genotypes. PMID: 18713828

Hide All

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Protein Families

Cytochrome P450 family

Tissue Specificity

Detected in the liver and lung (at protein level).

Database Links

HGNC: 2644

OMIM: 124075

KEGG: hsa:1580

STRING: 9606.ENSP00000360991

UniGene: Hs.436317

Promotions

CUSABIO Premium Active Proteins 20% OFF SALE

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
Please enter the characters shown. Click the image to refresh if unclear.

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address