DAZAP1 Antibody

1. Data indicate that DAZAP1 exerts a suppressive effect on cox6c pre-mRNA splicing and reduced DAZAP1 expression increases the COX6C protein level, leading to cell growth retardation. PMID: 29505834
2. The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration. PMID: 24452013
3. this study reports the mapping of a 42-amino acid segment (N42) at the N-terminus of DAZAP1 that is both necessary and sufficient for its transcription-dependent nuclear localization. PMID: 23111326
4. Data show that hnRNPA1/A2, HuR and DAZAP1 splicing factors and DHX36 RNA helicase bind to the ISE, with hnRNPA1 acting negatively and DAZAP1 positively on splicing selection PMID: 21858080
5. DAZAP1 can regulate mRNA translation. PMID: 21576381
6. data suggest that MEF2D/DAZAP1 and/or DAZAP1/MEF2D contribute to leukemogenesis by altering signaling pathways normally regulated by wild-type MEF2D and DAZAP1 PMID: 15744350
7. This study shows expression patterns of DAZAP1 in human corpus luteum cells and demonstrates the in vivo interaction of DAZ-like protein (DAZL) with DAZAP1. PMID: 16209998
8. DAZ cannot bind simultaneously to DAZAP1 and poly(A)-binding protein (PABP), and suggest that the phosphorylation-induced dissociation of DAZ and DAZAP1 may allow the former to stimulate translation by interacting with PABP. PMID: 16848763
9. The binding of the splicing factors hnRNPA1/A2 and DAZAP1 is the primary determinant of T6 BRCA1 exon 18 exclusion. PMID: 18391021
10. The results suggest that DAZAP1 is a component of complexes that are crucial for the degradation and silencing of mRNA. PMID: 19285026

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HGNC: 2683

OMIM: 607430

KEGG: hsa:26528

STRING: 9606.ENSP00000233078

UniGene: Hs.222510