DCAF6 Antibody

Code CSB-PA981190
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA981190(DCAF6 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA981190(DCAF6 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
DCAF6
Alternative Names
1200006M05Rik antibody; Androgen receptor complex associated protein antibody; Androgen receptor complex-associated protein antibody; ARCAP antibody; DCAF6 antibody; DCAF6_HUMAN antibody; DDB1 and CUL4 associated factor 6 antibody; DDB1- and CUL4-associated factor 6 antibody; IQ motif and WD repeat-containing protein 1 antibody; IQ motif and WD repeats 1 antibody; IQWD1 antibody; MSTP055 antibody; NRIP antibody; Nuclear receptor interaction protein antibody; RP4 745I14.1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthetic peptide of Human DCAF6
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Ligand-dependent coactivator of nuclear receptors. Enhance transcriptional activity of the nuclear receptors NR3C1 and AR. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Gene References into Functions
  1. High IQWD1 expression is associated with breast cancer. PMID: 24222117
  2. NRIP enhances HPV 16 gene expression via interaction with either GR or viral E2. PMID: 22177699
  3. NRIP interacts with either androgen or glucocorticoid receptors PMID: 15784617
  4. NRIP plays a feed-forward role enhancing androgen receptor (AR)-driven NRIP promoter activity via NRIP forming a complex with AR to protect AR protein from proteasome degradation. PMID: 17984071
  5. A survey results showed that ten cancer cases were revealed to express the NRIP in six malignancies, but not all of these specific tumor types consistently showed positive NRIP expression. PMID: 18673574

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Subcellular Location
Nucleus.
Tissue Specificity
Highly expressed in skeletal muscle and testis. Expressed to a lesser degree in heart, prostate, and adrenal gland.
Database Links

HGNC: 30002

OMIM: 610494

KEGG: hsa:55827

STRING: 9606.ENSP00000356814

UniGene: Hs.435741

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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